# Open TechEd: reconstructing NanoDrop 1000 USB control

> Open TechEd reconstructs USB control of the Thermo Fisher NanoDrop 1000 spectrophotometer. The pilot captures vendor-software traffic, documents command and data endpoints, calibration reads, lamp and clamp controls, and pixel decoding, then implements a Python driver used through PyLabRobot.

- Type: Case study
- Targets: Protocol
- Category: Independent reconstruction cases
- Relationship: Independent reconstruction project
- Sources reviewed: 2026-11-06
- Added to the catalog: 2026-11-08
- Original resource: <https://github.com/Vsaggiomo/open-teched-nanodrop>
- Primary source: <https://github.com/Vsaggiomo/open-teched-nanodrop/blob/67c9c99ef6efcaea46587f423206a42f715e0d1c/README.md>
- Catalog page: <https://awesomerea.org/resources/open-teched-nanodrop-case/>
- Record JSON: <https://awesomerea.org/resources/open-teched-nanodrop-case/record.json>
- Chinese version: [简体中文](https://awesomerea.org/zh/resources/open-teched-nanodrop-case/index.md)

## Requirements & limits

- **Prerequisites:** A NanoDrop 1000, Python, and an open USB driver are required for instrument control.
- **Testing evidence:** The investigation and demonstration cover one pilot instrument; the author reports a paracetamol absorbance measurement.
- **License:** MIT license.

## Primary sources

1. <https://github.com/Vsaggiomo/open-teched-nanodrop/blob/67c9c99ef6efcaea46587f423206a42f715e0d1c/README.md>
2. <https://github.com/Vsaggiomo/open-teched-nanodrop/blob/67c9c99ef6efcaea46587f423206a42f715e0d1c/demonstration/README.md>

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## About this entry

The description was reviewed against primary sources.
Original editorial content: MIT. Linked projects, papers and assets retain their own rights and licenses.